BE-23372M, a novel protein tyrosine kinase inhibitor. II. Physico-chemical properties and structure elucidation.

نویسندگان

  • S Tanaka
  • T Okabe
  • S Nakajima
  • E Yoshida
  • H Suda
چکیده

BE-23372M, a new protein tyrosine kinase inhibitor, has been obtained as a reddish orange solid. The compound, C17H12O6, HRFAB-MS: m/z 312.0625 (M)+, is an acidic substance, showing UV (MeOH) lambda max (epsilon) 266 (8,800), 426 nm (20,400), and IR (KBr)vmax 1752(C = O) and 3298(OH) cm-1. The structure of BE-23372M, (E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-fur anone, has been elucidated by 1H and 13C NMR studies.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 47 3  شماره 

صفحات  -

تاریخ انتشار 1994